Figure 7

Immunohistochemistry of 250 mm3 Normoxic and Hypoxic Tumor Xenografts. Tissue sections were probed with primary antibodies against the protein of interest, then labeled with Alexa Fluor® 488 conjugated secondary antibodies (green). F-actin was stained with Alexa Fluor® 568 phalloidin (red) and nuclei were stained with Hoechst 33342 (blue). These images represent protein expression in the tumor core.