Figure 4
From: BRCA1 Zinc RING Finger Domain Disruption Alters Caspase Response in Ovarian Surface Epithelial Cells
Effect of amino-terminal BRCA1 mutation on DNA repair protein expression. BRCA1wt and BRCA1+ cells were treated and lysed as in Figure 3 and probed for cleaved PARP (86 kDa) and ERCC1 (36 kDa). Membranes were then probed for actin for loading consistency. Images are representative of at least 3 independent treatments blotted twice.