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Fig. 1 | Cancer Cell International

Fig. 1

From: Methylmalonic acid promotes colorectal cancer progression via activation of Wnt/β-catenin pathway mediated epithelial–mesenchymal transition

Fig. 1

MMA promotes cell proliferation in CRC cells. A, B CCK-8 assay showed that MMA was the most significant metabolite promoting the proliferation of both HCT116 (A) and SW480 (B) cells. C–F EdU assay indicated that MMA was significant for the increasing proliferation in both HCT116 (C, E) and SW480 (D, F) cells. Magnification: × 200. G–I Colony formation assay indicated that cell colony formation was increased in both HCT116 (G, H) and SW480 (G, I) cells. (**P < 0.01, ***P < 0.001, ****P < 0.0001)

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Cancer Cell International

ISSN: 1475-2867

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