Fig. 3

Construction of the diagnostic model on the GSDME methylations. A Barplots of a diagnostic model for pan-cancers on the GSDME methylations, showing a ranking of importance for every CpGs in GSDME. B ROC curve of the high sensitivity and specificity in distinguishing different types of cancers from the matched normal tissues. C Unsupervised hierarchical clustering and heatmap of the profiles of GSDME methylations for these 22 CpGs among all samples of 23 cancers and the matched normal samples. Left color bars mark the tissues of cancer types