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Fig. 15 | Cancer Cell International

Fig. 15

From: A1, an innovative fluorinated CXCR4 inhibitor, redefines the therapeutic landscape in colorectal cancer

Fig. 15

The overall structure of CXCR4 (dimer) and the CXCR4 binding site (groove) for CXCL12, and the inhibitors binding pocket as well as a close view of the studied ligands interactions in the CXCR4 binding pocket; a. A1, b. ITD and c. AMD3100. Green dashes represent salt bridges, velvet dashes represent π- π electrostatic interactions, orange dashes represent π- cation and π- anion interactions, yellow dashes represent conventional hydrogen bonds, and light blue dashes represent halogen bonds

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Cancer Cell International

ISSN: 1475-2867

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