Fig. 5

The serum levels of ECM1 and GPNMB were significantly higher in DDLPS than in WDLPS, with ECM1 demonstrating a gradual increase across varying FNCLCC grades. (A) Serum protein levels of TIMP1, FN1, MMP11, GPNMB, and ECM1 in WDLPS and DDLPS patients. (B) ROC curve of the serum GPNMB, and ECM1 levels and the combination of the two biomarkers for patients with WDLPS or DDLPS. (C) Serum protein levels of GPNMB and ECM1 in the FNCLCC G1 WDLPS, G2, and G3 DDLPS. n = 35 patients for the WDLPS group, and n = 93 patients for the DDLPS group