Table 2 Results from the Cox Proportional Hazard models on OS

Patient’s age (y)

1.019

0.991–1.049

0.181

Sex

0.08

Female vs. male

0.597

0.335–1.064

Tumor size (cm)

1.018

0.990–1.047

0.209

FNCLCC grade

< 0.001***

0.023*

DD G2 vs. G1 WD

2.433

0.958–6.176

2.025

0.736–5.570

DD G3 vs. G1 WD

5.518

2.268–13.424

3.897

1.393–10.903

Presentation

0.022*

Recurrent vs. Primary

1.928

1.101–3.376

Surgical margin

< 0.001***

< 0.001***

R2 vs. R0 + R1

7.470

3.520–15.853

7.142

2.816–18.115

FN1 (ng/mL)

1.001

0.999–1.003

0.341

TIMP1 (ng/mL)

1.022

1.004–1.041

0.018*

MMP11 (ng/mL)

0.996

0.993–1.000

0.036*

GPNMB (ng/mL)

1.044

1.028–1.061

< 0.001***

1.027

1.004–1.050

0.019*

ECM1 (ng/mL)

1.002

1.001–1.003

< 0.001***