Table 3 Results from the Cox Proportional hazards models on RFS

Patient’s age (y)

1.005

0.976–1.035

0.741

Sex

0.113

Female vs. male

0.609

0.330–1.124

Tumor size (cm)

1.014

0.980–1.048

0.433

FNCLCC grade

0.001**

0.027*

DD G2 vs. G1 WD

3.576

1.322–9.668

2.650

0.939–7.481

DD G3 vs. G1 WD

6.181

2.303–16.586

4.361

1.479–12.858

Presentation

0.001**

0.046*

Recurrent vs. Primary

2.752

1.483–5.109

1.962

1.013–3.801

FN1 (ng/mL)

1.000

0.998–1.003

0.752

TIMP1 (ng/mL)

1.013

0.993–1.034

0.201

MMP11 (ng/mL)

0.998

0.994–1.001

0.079

GPNMB (ng/mL)

1.002

0.970–1.034

0.922

ECM1 (ng/mL)

1.002

1.001–1.003

< 0.001***

1.001

1.000–1.003

0.043*