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Table 1 Baseline demographic and clinical characteristics of included patients with breast disease

From: Evaluation of functional magnetic resonance APT and DKI imaging for breast cancer

Characteristic

Benign lesions (n = 55)

Malignant lesions (n = 113)

P value

Patient characteristic

   

Patient age (year)

45.2 ± 8.7

48.7 ± 9.0

0.017

Menstrual status

  

0.044

Premenopausal (n = 104)

40 (72.7%)

64 (56.6%)

 

Postmenopausal (n = 64)

15 (27.3%)

49 (43.3%)

 

Lesion characteristic

  

0.0486

Size (cm)

2.72 ± 2. 21

3.35 ± 1.72

 

Masses

28 (50.9%)

96 (85.0%)

 

Shape

  

<0.0001

Oval or round (n = 45)

37 (67.3%)

8 (7.1%)

 

Irregular (n = 123)

18 (32.7%)

105 (92.9%)

 

Kinetic curve type

  

<0.0001

Persistent

9

0

 

Plateau

22

12

 

Washout

12

98

 

Others

12

3

 

BI-RADS

  

<0.0001

Negative (categories 1, 2, and 3)

31 (56.4%)

0 (0.0%)

 

Positive (categories 4, 5, and 6)

18 (32.7%)

113 (100.0%)

 

Parameters

   

Kapp

0.53 ± 0.20

0.92 ± 0.31

<0.0001

Dapp (×10− 3 mm2/s)

1.98 ± 0.65

1.15 ± 0.52

<0.0001

MTRasym (3.5 ppm)

2.27 ± 1.36

2.78 ± 1.24

0.0173

ADC (×10− 3 mm2/s)

1.46 ± 0.46

0.79 ± 0.24

<0.0001

  1. ADC, apparent diffusion coefficient; BI-RADS, breast imaging reporting and data system; Dapp, apparent diffusivity; Kapp, apparent kurtosis coefficient; MTRasym (3.5 ppm), asymmetric magnetization transfer ratio at 3.5 ppm