Fig. 12

KRT81 promotes EMT and PI3K/AKT pathway activation. A WB detection of EMT-associated proteins (E-cadherin, N-cadherin, and Vimentin) after KRT81 knockdown. B, C KEGG and GSEA enrichment analysis of up-regulated DEGs. D WB detection of p-PI3K, PI3K, p-AKT, and AKT proteins levels in A549 cells after siNC, siRNA2 transfections.*p < 0.05, **p < 0.01