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Table 4 Mean tumor growth time, delay time and inhibition rate in MB49 tumor-bearing mice after treatment with different doses of lenvatinib

From: Mechanistic insights of lenvatinib: enhancing cisplatin sensitivity, inducing apoptosis, and suppressing metastasis in bladder cancer cells through EGFR/ERK/P38/NF-κB signaling inactivation

Analysis methods

Lenvatinib

0 mg/kg

5 mg/kg

10 mg/kg

MTGT (day)*

6.35

15.63

30.08

MTGDT (day)#

na

9.28

23.73

MGIR$

na

2.46

4.74

  1. na: not available
  2. *Mean tumor growth time (MTGT): the time at which the MB49 tumor volume reached 500 mm3. #Mean tumor growth delay time (MTGDT): the mean MB49 tumor growth time of the treated group minus that of the control group (0 mg/kg lenvatinib, 0.1% DMSO, CTRL). $Mean growth inhibition rate (MGIR): the mean MB49 tumor growth time of the lenvatinib-treated group/the mean MB49 tumor growth time of the control group