Table 1 List of ongoing clinical studies to evaluate CTCs in HCC patients after different interventions

1

57

TACE

A decrease in CTC count after surgery indicates that postoperative TACE is effective in preventing the recurrence of HCC/Completed

NCT02032368

2

220

Propofol, Sevoflurane

Recruiting

NCT04601961

3

150

1.curative surgery or radiofrequency ablation therapy 2. TACE 3. systemic therapy

Recruiting

NCT01930383

4

184

FOLFOX4(infusional FU, LV, and OXA)

Recruiting

NCT04521491

5

45

Radiotherapy

Recruiting

NCT02066974

6

200

Hepatic resection

Recruiting

NCT04800497

7

100

Sorafenib

Completed

NCT01481805

8

300

CTC Capture for early diagnosis and postoperative tumor recurrence monitoring of liver Cancer /Recruiting

NCT04688606

9

37

Durvalumab + SBRT

Recruiting

NCT04913480

10

50

PD-1/ Sorafenib

Recruiting

NCT04152356

11

200

Recruiting

NCT02036216

12

256

TACE/ Epirubicin/ lipiodol

Not yet recruiting

NCT02631499

13

40

-

Recruiting

NCT04506398

14

20

IRE & multiple NK immunotherapies

Completed

NCT03008343

15

167

Sorafenib, RFA or surgery, Everolimus, Lanreotide

Completed

NCT02973204

16

25

Temsirolimus

Recruiting

NCT01567930

17

18

COMBIG-DC (ilixadencel)

Completed

NCT01974661