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Fig. 3 | Cancer Cell International

Fig. 3

From: Protein kinase CK2 sustains de novo fatty acid synthesis by regulating the expression of SCD-1 in human renal cancer cells

Fig. 3

RNA-seq analysis of differentially expressed genes regulating SCD-1 expression following pharmacological inhibition of CK2. (A) A-498 and A-498-SR cells were treated with vehicle (DMSO, Control) or 10 µM CX-4945 for 24 h, respectively. Total RNA was isolated and employed for RNA-seq. Boxplots show the mRNA levels of major transcription factors regulating the expression of SCD-1. Results highlight the effect of adaptation to sunitinib treatment and the response to CK2 inhibition of the indicated ccRCC cell lines

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Cancer Cell International

ISSN: 1475-2867

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