Fig. 1

TUBB2B is upregulated in GBM tissues. (A-B) Based on GEPIA database analysis, TUBB2B was significantly upregulated in LGG and GBM; P < 0.05. (C-E) Prognostic value of TUBB2B in TGGA, CGGA, Rembrandt datasets. (F) Immunohistochemical detection of TUBB2B protein levels in glioma tissues and normal brain tissues (Scale bar, 200 μm). (G) Expression of TUBB2B in 8 normal tissues and 80 GBM tissues. (H) Kaplan Meier analysis was used to evaluate the overall survival of GBM patients based on TUBB2B expression (n = 64, **P = 0.0073). All results are displayed as the mean ± SD. p < 0.05, *; p < 0.01, **; p < 0.001, ***