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Fig. 5 | Cancer Cell International

Fig. 5

From: TUBB2B regulates epithelial-mesenchymal transition via interaction with Vimentin to promote glioma migration and invasion

Fig. 5

TUBB2B interacts with Vimentin in GBM cells (A) STRING database protein interaction network of TUBB2B. (B) The interaction between TUBB2B and Vimentin inLN229 and T98 cells was determined using Co-IP. (C) Double staining of GBM cells with TUBB2B and Vimentin was assessed using confocal microscopy (Scale bar, 10 μm. Pearson’s R value = 0.60). (D) The predicted binding mode of TUBB2B and Vimentin, as well as the detail interactions between two proteins. (E) Schematic representation of Flag-TUBB2B-NC and the Flag-TUBB2B mutants. All results are displayed as the mean ± SD. p < 0.05, *; p < 0.01, **; p < 0.001, ***; p < 0.0001, ****

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Cancer Cell International

ISSN: 1475-2867

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