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Fig. 8 | Cancer Cell International

Fig. 8

From: Heterogeneous nuclear ribonucleoprotein C promotes non-small cell lung cancer progression by enhancing XB130 mRNA stability and translation

Fig. 8

Overexpression of XB130 reverses effects of hnRNPC silencing on cell proliferation and EMT. Control (Lv151) or XB130 overexpression recombinant vectors (Lv151-XB130) were transfected into control or hnRNPC-silenced cells. A: Western blotting assessed protein expression levels of XB130 and hnRNPC. B: RTCA assays monitored cell growth. C: Adherent colony formation assays evaluated the cloning ability of cells. D: Wound healing assays investigated cell migration. E: Invasion assays assessed the invasive capability of the cells. F-G: Western blotting analyzed the expression of EMT-related markers (F), as well as total Akt and p-Akt (Ser473) (G) in cells. GAPDH was used as a loading control. * p < 0.05, ** p < 0.01, *** p < 0.001

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Cancer Cell International

ISSN: 1475-2867

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