Fig. 8

Analysis of somatic mutation and copy number variation (CNV). (A) Waterfall plots of the top 20 mutated genes in the low- and high-DCRGS subgroups. (B, C) Forest and bar graphs of differentially mutated genes in both subgroups. (D) Variations in the mutation loads of the two subgroups (left) and the connection between the mutation loads and DCRGS (right); denser points are shown by redder colors in the plot. (E) GSEA of differentially mutated genes. (F) Violin plots of amplification and deletion mutations between the two subgroups. (G) CNV plot demonstrating the gistic score and the mutation frequency distribution in both subgroups