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Fig. 1 | Cancer Cell International

Fig. 1

From: Overexpression of metalloproteinase PAPPA accelerates cancer progression and correlates with immune cell infiltration in gastric cancer: insights from bioinformatics and in vitro investigations

Fig. 1

Expression and prognosis analysis of PAPPA in the database. A PAPPA gene expression in STAD and normal tissues from the TCGA database revealed a notable upregulation of PAPPA in tumors compared to normal tissues. B Relative expression levels of PAPPA in 415 GC tissues and 34 normal tissues from TCGA database. C The expression levels of PAPPA vary across different stages of GC tissues, with a positive correlation observed between PAPPA expression and tumor stage progression. D Expression levels of the PAPPA gene across various grades of GC tissues demonstrate a positive correlation with tumor grading, with the highest expression observed at grade 3. E Comparing GC tissues to normal tissues, PAPPA expression was elevated in with or without lymph node metastasis *P < 0.05, **P < 0.01, ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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