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Fig. 5 | Cancer Cell International

Fig. 5

From: Clinical relevance of macromolecular complexes involving integrins, potassium and sodium ion channels and the sodium/proton antiporter in human breast cancer

Fig. 5

In-silico network and survival analyses of SLC9A1, KCNH2, ITGB1 and SCN5A in BCa samples. A) Network analysis of SLC9A1, KCNH2, ITGB1 and SCN5A, and in BCa datasets. The genes of interest (seed genes) are indicated by red stars while circles represent the correlated genes. Pearson Correlation Threshold:0.46; Top genes: 15. The analysis was performed with GeneFriends [23]. B-E) Survival analysis of in-silico BCa cohort (N = 1203). Kaplan Meier plots of OS for SLC9A1 (panel B), KCNH2 (panel C), ITGB1 (panel D) and SCN5A (panel E). Blue curves: high expression; Orange curves: middle expression; Green curves: low expression. The in-silico analyses were carried out through in a TCGA BCa dataset retrieved by UCSC Xena Browser

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Cancer Cell International

ISSN: 1475-2867

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