Fig. 2

Expressions of extracellular signal-regulated kinase 2 (ERK2) and its phosphorylated form p-ERK2 in clinical BC patients and the relationship between p-ERK2 and ferroptosis. A The expression of ERK2 in normal and BC patients. B The survival time of BC patients with a high or low level of ERK2 expression. C The expressions of ERK2 and p-ERK2 in BC tissues (n = 7) were detected by western blotting (WB). D P-ERK immunohistochemical (IHC) staining in tumor tissues of BC patients and its quantitation. E The expressions of solute carrier family 7 member 11 (SLC7A11) and glutathione peroxidase 4 (GPX4) in BC tissues (n = 7) were detected by WB. F The correlation analysis of ERK2 and SLC7A11, n = 7. G The correlation analysis of p-ERK2 and SLC7A11, n = 7. **p < 0.01, ***p < 0.001