From: Non-coding RNAs, a double-edged sword in breast cancer prognosis
microRNA name | Function | Interactions | References |
---|---|---|---|
miR-17-5p | Cancer progression and cell proliferation | Interaction with HBP1 and Wnt/β-catenin | |
miR‑93 | EMT, promotes cancer | Interaction with E‑cadherin and occluding, EYA2 | |
miR-214 | Cancer progression, emergence of drug resistance | interaction with MT1JP and RUNX3 | |
miR-301 | Cancer progression, decreases survival rates | CPEB1/SIRT1/SOX2 | |
miR-9 | Angiogenesis, poor prognosis in patients, EMT [391] | Interaction with Sphingosine-1- Phosphate Receptor 1 [392], JAK‐STAT pathway [393] | |
MiR-373 | EMT, cancer progression | Interaction with TXNIP-HIF1α-TWIST axis [394], VEGF and cyclin D1 genes [395] | |
Let-7a | Hindering growth and migration, blocks the self-renewal of breast cancer stem cells | Interaction with HMGA1 [396], Inhibiting estrogen-activated Wnt [397] | |
miR-542-3p | Inhibits angiogenesis | Angiopoietin-2 | [398] |
miR-205 | weakens breast cancer stemness | jagged1 | [399] |
miR-148a/152 | Inhibiting tumor proliferation and angiogenesis | IGF-IR and IRS1 | [400] |
miR-31 | Reduces metastasis and progression | Interaction with WAVE3 | [401] |
miR-290 | Apoptosis, suppresses progression | Targets Arid4b | [402] |