Skip to main content

Table 4 microRNAs associated with cancer

From: Non-coding RNAs, a double-edged sword in breast cancer prognosis

microRNA name

Function

Interactions

References

miR-17-5p

Cancer progression and cell proliferation

Interaction with HBP1 and Wnt/β-catenin

[383, 384]

miR‑93

EMT, promotes cancer

Interaction with E‑cadherin and occluding, EYA2

[385, 386]

miR-214

Cancer progression, emergence of drug resistance

interaction with MT1JP and RUNX3

[387, 388]

miR-301

Cancer progression, decreases survival rates

CPEB1/SIRT1/SOX2

[389, 390]

miR-9

Angiogenesis, poor prognosis in patients, EMT [391]

Interaction with Sphingosine-1- Phosphate Receptor 1 [392], JAK‐STAT pathway [393]

[391,392,393]

MiR-373

EMT, cancer progression

Interaction with TXNIP-HIF1α-TWIST axis [394], VEGF and cyclin D1 genes [395]

[394, 395]

Let-7a

Hindering growth and migration, blocks the self-renewal of breast cancer stem cells

Interaction with HMGA1 [396], Inhibiting estrogen-activated Wnt [397]

[396, 397]

miR-542-3p

Inhibits angiogenesis

Angiopoietin-2

[398]

miR-205

weakens breast cancer stemness

jagged1

[399]

miR-148a/152

Inhibiting tumor proliferation and angiogenesis

IGF-IR and IRS1

[400]

miR-31

Reduces metastasis and progression

Interaction with WAVE3

[401]

miR-290

Apoptosis, suppresses progression

Targets Arid4b

[402]