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Fig. 7 | Cancer Cell International

Fig. 7

From: Expression of stearoyl coenzyme a desaturase in neuronal cells facilitates pancreatic cancer progression

Fig. 7

The effect of SCD expression on the proliferation and migration ability of PDAC cells. (A) The efficacy of the SCD knockdown in Schwann cells was evaluated through IB assays. The knockdown was indicated as sgScramble, sgSCD-1, sgSCD-2 and sgSCD-3. GAPDH was employed as a loading control. (B) mRNA expression levels of SCD in sgScramble vs. sgSCD. (C) Schematic representation of Schwann Cells and PDAC Cells in co-culture mode. (D) Cell viability assay detection of PDAC cells (PANC-1 and MIA PaCa-2) co cultured with SCD knockdown Schwann cells. (E) Wound healing assay of PDAC cells co cultured with SCD knockdown Schwann cells. (F) The relative percentage of cells exhibiting SCD-induced invasion in PDAC cells (PANC-1 and MIA PaCa-2), ***p < 0.001

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Cancer Cell International

ISSN: 1475-2867

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