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Table 3 The summary of research on cuproptosis-associated RNA biomarkers in HCC

From: Cuproplasia and cuproptosis in hepatocellular carcinoma: mechanisms, relationship and potential role in tumor microenvironment and treatment

Researchers

Biomarkers of RNA

Findings and Significance of the Research

References

Genhao Zhang et al

lncRNAs (AC099329.2, AC138904.1, AC145343.1, DNMBP-AS1, DEPDC1-AS1, GIHCG)

Selected six lncRNA linked to cuproptosis and built a lncRNA profile to predict the prognosis of immunotherapy in HCC

165

Qiongyue Zhang et al

lncRNAs (AC003093.1, AC015819.1, AL122035.1, AL590705.3, and MKLN1-AS)

Selected five lncRNAs that could be used in HCC immunotherapy and targeted therapy evaluation, immune cell activity, and function prediction

171

Hongfei Zhu et al

lncRNAs (AC005479.2, AC009974.2, GSEC, AC026412.3, AC245060.7, AL031985.3, AL158166.1, AL365361.1, LINC00426)

Built the CRlncSig to predict the prognosis of immunotherapy in HCC

164

Shujia Chen et al

lncRNAs (AC019069.1, AC079209.1, AC105020.5, HCG15, LINC01515)

Those lncRNAs are associated with TME and expressions of key immune checkpoints

163

Lan Luo et al

lncRNAs (AC012073.1, AC099850.3, AL031985.3, KDM4A-AS1, MIR210HG, MKLN1-AS, and PLBD1AS1)

Built the CRLRSM, and the high expression of these 7 lncRNAs is associated with poor prognosis in HCC

162

Ze Jin et al

miRNAs

The first research focused on miRNAs of cuproptosis in HCC and the CRMs associated with the prognosis of HCC

172

  1. CRlncSig cuproptosis-related lncRNA signature, CRLRSM cuproptosis-related lncRNAs risk-scoring model, CRMs cuproptosis-related miRNAs, HCC hepatocellular carcinoma, lncRNA long non-coding RNA