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Fig. 9 | Cancer Cell International

Fig. 9

From: CircRNA hsa_circ_0004781 promoted cell proliferation by acting as a sponge for miR-9-5p and miR-338-3p and upregulating KLF5 and ADAM17 expression in pancreatic ductal adenocarcinoma

Fig. 9

Effects of real hsa_circ_0004781 on cell proliferation and the expression of miR-9-5p, miR-338-3p, KLF5, and ADAM17 in PDAC cells. AsPC-1 cells were transfected with control RNA (Ctr) or real hsa_circ_0004781 (real c4781) for 24 h. (A) Cell proliferation was determined using a CCK-8 assay. (B, C) Total RNA was extracted, and the expression of (B) miR-9-5p and miR-338-3p as well as (C) KLF5 and ADAM17 mRNA was detected through RT-qPCR. Values are presented as the mean ± SE from three independent experiments. *p < 0.05, **p < 0.01, #p < 0.001, ##p < 0.0001 vs. Ctr

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Cancer Cell International

ISSN: 1475-2867

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