Fig. 16

BAMBI promotes the proliferation, invasion and migration of HCC cells. A Western blot analysis showed that in HepG2 and MHCC-97H cells BAMBI can be stably knocked down by both shRNAs, and the expression of NRP1 and VTCN1 was positively correlated with BAMBI expression. B, C CCK8 assay showed that the viability of HepG2 and MHCC-97H cells was significantly inhibited after BAMBI knockdown compared with the control group. D, E Edu assay showed that the proliferation rate of HepG2 and MHCC-97H cells was significantly inhibited after BAMBI knockdown compared with the control group. F, G Wound healing assay showed that the rate of wound healing was significantly inhibited in HepG2 and MHCC-97H cells after BAMBI silencing. H, I Transwell assays indicated that BAMBI knockdown was inhibited Cell invasion ability of HepG2 and MHCC-97H cells. J, K The colony formation ability of the control group and BAMBI knockdown group was compared