Fig. 2
From: Targeting the USP7-CDK1 axis suppresses estrogen receptor-positive breast cancer progression
USP7 induces the proliferation of ERPBC cells. (A) USP7 expression in MCF7 (upper) and T47D (lower)-USP7-silenced cells. (B) Quantitative analysis of USP7 protein levels in ERPBC cell lines with USP7 suppression. (C) The proliferation ability of MCF7 (left) and T47D (right) cells with USP7 knockdown assessed via MTT assays in a time-dependent manner. (D) Proliferation of MCF7- (left) and T47D- (right) USP7–silenced cells assessed via BrdU incorporation assay. (E) Growth of MCF7- (left) and T47D- (right) USP7-silenced cells assessed via tumor formation assay. (F) Quantitative analysis of MCF7 (left) and T47D (right) cell growth with USP7 silencing using a tumor formation assay