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Fig. 5 | Cancer Cell International

Fig. 5

From: Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1

Fig. 5

Combination therapy suppressed the proliferation and enhanced ROS generation in leukemic cells. BrdU technique was used to evaluate the suppressive impact of different therapeutic agents on the proliferation of CLL cells (a). ELISA assay was employed to levels of ROS generation in both PBMCs and BMMCs after treatment with various therapeutic groups (b). The correlation between ROS and caspase 9 was evaluated in CLL cells (c)

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Cancer Cell International

ISSN: 1475-2867

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