Fig. 2

Flow cytometric analysis of immune cells in blood of healthy donors and BC patient samples. (A) Immune cell infiltration in the tumor tissue are displayed. (B) Mean proportions of T lymphocytes (grey), B lymphocytes (orange), myeloid cells (green), NK cells (blue), NK-T cells (red) in blood and tumor samples are displayed. (C) CD4⁺ and CD8⁺ T cell proportion of CD3⁺ T cells are given for TNBC, Luminal B, HER2⁺ in comparison to healthy donors. Data are shown as mean +/-SD and p-values were calculated by Kruskal-Wallis-test (Dunn´s multiple comparisons test) or one-way ANOVA (Tukey´s multiple comparisons test) based on parametric pretesting; * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001; **** p ≤ 0.0001; HD = peripheral blood of healthy donors; PB = patient derived peripheral blood; PT = patient derived tumor