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Table 2 Inorganic nanocarriers

From: Harnessing exosomes for targeted drug delivery systems to combat brain cancer

Nanocarrier

Advantages

Disadvantages

Mesoporous Silica

Highly stable; easily functionalized for targeted delivery (e.g., across the blood–brain barrier)

Limited biocompatibility without surface modification; potential for toxicity

Magnetic Nanoparticles

Excellent biocompatibility; enable magnetic field-based targeting; effective for hyperthermia treatments

Size and heating control during hyperthermia are challenging; toxicity concerns

Gold Nanoparticles

High electron density; easy conjugation with biomolecules; surface-enhanced Raman scattering capabilities

Expensive synthesis; potential biosafety concerns; limited scalability

Carbon Nanotubes

High drug-loading capacity; superior transmembrane capabilities

Cytotoxicity; poor dispersibility; surface functionalization challenges