Fig. 4

Identification of Potential Macrophage Subtypes in BC. A Venn diagram of core metagenes for M_Macrophage-SPP1-C1Q. B Consensus clustering in the METABRIC cohort based on 37 core metagenes. C Box plot illustrating the varying estimated proportions of M_Macrophage-SPP1-C1Q across different subtypes. D Heatmap of core metagenes of M_Macrophage-SPP1-C1Q and clinical features. E Alluvial diagram depicting the interrelations among BC patient subtypes, survival status, and Claudin subtype. F, G Kaplan–Meier analysis of OS (F) and relapse-free period (G) for BC patients belonging to two different molecular clusters. H Univariate and multivariate analyses of the association between clinical-pathological features and macrophage subtypes in the METABRIC cohort