Fig. 1

Response of Caco2 and HT-29 CRC cell lines to cytotoxic effects of 5-FU. Caco2 and HT-29 cells exhibited cytotoxic responses at concentrations of 50 ng/ml or higher of 5-FU. The IC50 values for 5-FU in Caco2 and HT-29 cells were determined to be 353.4 ng/ml and 543.3 ng/ml, respectively