Fig. 11

Gene interaction network of common differentially expressed genes. The network illustrates the interactions between 11 genes significantly enriched in KEGG pathways, including MicroRNAs in cancer, signaling pathways regulating pluripotency of stem cells, and Proteoglycans in cancer. Each node represents a gene, and the edges represent known or predicted interactions, categorized as experimentally determined (pink), curated from databases (blue), or predicted through gene neighborhood, co-expression, and text mining (green, black, and yellow respectively). Key players such as MYC, CD44, PROM1, and SOX2 are central to the network, indicating their collaborative roles in the pathways analyzed