Table 2 The percentage of CRC stemness surface markers, CD44, CD166, and CD133, expressed in cells exposed to 5-FU and spheroids, in comparison to their parental cells

CD44

1.325 ± 0.24

95.99 ± 0.29^****

40.92 ± 0.17^****

1.685 ± 0.16

94.19 ± 1.11^****

12.5 ± 9.61

CD133

0.53 ± 0.07

24.6 ± 1.83^***

35.82 ± 10.71^****

1.365 ± 0.02

12.85 ± 1.34

8.345 ± 4.81

CD166

1.285 ± 0.04

5.8 ± 0.98

37.47 ± 0.45^****

1.57 ± 0.12

5.42 ± 0.67

13.05 ± 10.45