Table 3 The IPA pathways linked to the shared differentially expressed genes in 5-FU exposed subpopulations of CRC cells
Gene set | Pathway | Overlap | P-value | Adjusted P-value | Odds Ratio | Combined Score | Genes |
|---|---|---|---|---|---|---|---|
KEGG_2019_Human | MicroRNAs in cancer | 3/299 | 0.000847 | 0.011005 | 19.95709 | 141.1835 | ABCB1; ZEB1; CD44 |
KEGG_2019_Human | Pluripotency of stem cells | 2/139 | 0.003557 | 0.023123 | 26.34373 | 148.545 | SOX2; KLF4 |
KEGG_2019_Human | Proteoglycans in cancer | 2/201 | 0.007288 | 0.031581 | 18.07949 | 88.97873 | TWIST1; CD44 |