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Fig. 4 | Cancer Cell International

Fig. 4

From: LncRNA SPINT1-AS1 enhances the Warburg effect and promotes the progression of osteosarcoma via the miR-135b-5p/PGAM1 axis

Fig. 4

SPINT1-AS1 functions as a sponge of miR-135b-5p. A Putative binding sites between SPINT1-AS1 and miR-135b-5p. B The miR-135b-5p expression increased in OS cells transfected with SPINT1-AS1 shRNA. C, D AGO2-RIP followed by qPCR to detect SPINT1-AS1 level after miR-135b-5p overexpression. E, F Luciferase activity of OS cells in luciferase reporter plasmid containing wild-type SPINT1-AS1 3ʹ-UTR and mutant SPINT1-AS1 3ʹ-UTR co-transfected with miR-135b-5p mimics or negative control was detected. *p < 0.05; **p < 0.01; ***p < 0.001 (Student's t-test)

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Cancer Cell International

ISSN: 1475-2867

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