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Fig. 5 | Cancer Cell International

Fig. 5

From: LncRNA SPINT1-AS1 enhances the Warburg effect and promotes the progression of osteosarcoma via the miR-135b-5p/PGAM1 axis

Fig. 5

Upregulation of miR-135b-5p inhibited the tumor progression and aerobic glycolysis in OS cells. A Expression of miR-135b-5p was measured in miR-135b-5p-transfected or control OS cells. B, C The proliferation of OS cells after overexpressing miR-135b-5p. D Colony formation assay of OS cells after overexpressing miR-135b-5p. E, F Wound healing assay of OS cells after overexpressing miR-135b-5p (scale bar, 100 μm). G Transwell assay of OS cells after overexpressing miR-135b-5p (scale bar, 50 μm). H–J Glucose consumption, lactate production and pyruvate production of OS cells transfected with miR-135b-5p or control was presented. *p < 0.05; **p < 0.01; ***p < 0.001 (Student's t-test)

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Cancer Cell International

ISSN: 1475-2867

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