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Fig. 1 | Cancer Cell International

Fig. 1

From: A novel mitochondrial quality regulation gene signature for anticipating prognosis, TME, and therapeutic response in LUAD by multi-omics analysis and experimental verification

Fig. 1

The genetic and transcriptional modifications of 20 MQRGs in LUAD. (A) Analysis of 20 MQRGs that are differentially expressed between normal and LUAD specimens. (B) The MQRGs somatic mutation frequency in the TCGA cohort. (C) Determining the positions of CNV modifications in MQRGs on 23 chromosomes. (D) Ascertaining CNV gain, loss, and non-CNV Frequencies of MQRGs. (E) Correlation analysis for the MQRGs. (F) Interactions between MQRGs in LUAD. The MQRGs interaction is shown as a line, with the line thickness indicating the link intensity. The pink and blue lines on the graph indicate positive and negative connections, respectively. MQRGs, mitochondrial quality-related genes; LUAD, lung adenocarcinoma; TCGA, The Cancer Genome Atlas; CNV, copy number variant; *p < 0.05; **p < 0.01; ***p < 0.001

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Cancer Cell International

ISSN: 1475-2867

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