Fig. 4

The application of diagnostic model in different urothelial cancer stages. A The correctly detected numbers (true positive numbers) of three single-gene diagnostic markers and their overlaps. B The true positive number and the sensitivity of three-marker diagnostic model in different clinical stages of the 108 UC patients in model-testing cohort. C Sankey diagram showing the component and the grouping trend of different ways of classification. The cases included all urine samples used in the study, except for the 30 cases lacking definite staging information. V represents for VIM. T represents for TMEM220. P represents for PPM1 N. D HE-staining pictures of tumor tissues sections. Histological photos of 6 representative cases were presented, 2 cases of stage 0a – stage I, 2 cases of stage II, and 2 cases of stage III – stage IV. Scale bar represents for 300 μm