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Fig. 7 | Cancer Cell International

Fig. 7

From: Single-cell transcriptome sequencing reveals the mechanism of Realgar improvement on erythropoiesis in mice with myelodysplastic syndrome

Fig. 7

Enrichment analysis of differentially expressed genes in erythroblasts in vitro and analysis of the intersection of in vivo and in vitro differentially expressed genes. (A) Volcano plot displaying DEGs, with red dots representing significantly upregulated genes (P ≤ 0.05, |Log2 FC|≥ 0.25) and blue dots indicating significantly downregulated genes (P ≤ 0.05, |Log2 FC|≥ 0.25). The top 10 DEGs are labeled. (B) KEGG enrichment analysis of upregulated DEGs in the As2S2 vs. Control comparison. (C) Venn diagram showing the overlap of upregulated DEGs in erythroblasts between Realgar vs. NHD13 (in vivo) and As2S2 vs. Control (in vitro) comparisons, with 17 overlapping genes identified. (D) GO enrichment analysis of the overlapping upregulated genes. (E) KEGG enrichment analysis of the overlapping upregulated genes. (F) Reactome enrichment analysis of the overlapping upregulated genes

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Cancer Cell International

ISSN: 1475-2867

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