Table 4 Databases for predicting the potential regulatory mechanisms of circRNA

CSCD 2.0

Predicting the interactions of circRNA-miRNA and circRNA-RBP

http://geneyun.net/CSCD2/

[91]

CircNet 2.0

Providing circRNA-miRNA-gene regulatory network

https://awi.cuhk.edu.cn/~CircNet

[92]

Circ2Disease

Providing circRNA-miRNA-gene regulatory networks in human diseases

http://bioinformatics.zju.edu.cn/Circ2Disease/index.html

[95]

CircRic

Analyzing the regulators in circRNAs biogenesis and effect of circRNAs on drug response. Providing the association between circRNAs with mRNA, protein and mutation. Predicting RBP and miRNA binding site in circRNAs

https://hanlab.uth.edu/cRic

[97]

Circbank

Providing miRNA-circRNA interactions and circRNA mutation information

http://www.circbank.cn

[104]

CircInteractome

Predicting the binding sites for RBPs and miRNAs on reported circRNAs

http://circinteractome.nia.nih.gov

[115]

CircFunBase

Providing visualized circRNA-miRNA and circRNA-RBPs interaction networks and function information of circRNAs

http://bis.zju.edu.cn/CircFunBase

[116]

ENCORI

Providing RBP-circRNA interactions which are supported by CLIP-seq data

https://rnasysu.com/encori/index.php

[117]

TRCirc

Integrating current transcription factors binding sites and circRNA annotations. Also, providing other information of circRNAs,such as methylation level, H3 K27ac signals, enhancers and expression

http://www.licpathway.net/TRCirc

[118]