Fig. 5

Identifying therapeutic targets for OS patients. (A) The heatmap of ten RGPSM-related genes in the high- and low-RGPSM patients. (B) The feature plots of six high expressed genes. (C) The K-M plots of PSIP1 in predicting the prognosis of OS patients in various cohorts. (D) The PSIP1 mRNA expression levels between normal samples (normal, N)/cells (osteoblast, OB; mesenchymal stem cell, MSC) and tumor (T)/OS cells. (E) The PSIP1 protein levels in hFOB1.19 and OS cells. *, p < 0.05; **, p < 0.01