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Fig. 6 | Cancer Cell International

Fig. 6

From: Identifying PSIP1 as a critical R-loop regulator in osteosarcoma via machine-learning and multi-omics analysis

Fig. 6

Silencing PSIP1 inhibited proliferation, invasion and migration of OS. (A-B) CCK8 (A) and colonies plate information assays (B) were used to measure the effects of silencing or up-regulating PSIP1 in OS cells. (C) Transwell migration assays were used to detect the migratory ability of OS cells with silencing or up-regulating PSIP1. (D) The subcutaneous tumor morphology after knockdown of PSIP1. (E-F) The size (E) and weight (F) of tumors. (G) The HE results and IHC results of PSIP1 and Ki-67 of subcutaneous tumors

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