Fig. 5

Interaction network of DEpiRNA and their predicted target genes in WT. (a) Network of the DEpiRNA target genes and their enrichment in various GO biological processes, KEGG, and WikiPathways. In this network, small circles represent the target genes of piRNA, while large colored circles indicate the most highly enriched terms of biological processes, KEGG pathways, and WikiPathways mediated by the piRNA targets. This network was constructed using Cytoscape software, incorporating the CluePedia plugin for pathway insights based on integrated experimental and in silico data. (b) Interaction network of DEpiRNA and their potential targets, as identified by the miRanda algorithm and visualized in Cytoscape. Upregulated piRNA are shown in blue and their targets in light blue, while downregulated piRNA are in orange with corresponding targets in light orange