Fig. 5

Characterization of myeloid cells between PD group and PR group. A UMAP projection of subclustered myeloid cells from 9 treatment-naive ES-SCLC samples. Each dot corresponds to a single cell, colored by cell type and group. B Heatmap of marker gene expression in myeloid cell subtypes. C The proportion of myeloid cell subtypes among three groups. D Differentially expressed pathways are scored per cell by GSVA among myeloid cell subtypes. E Potential developmental trajectory of myeloid cells inferred by Monocle. Each dot corresponds to a single cell, colored by pseudotime value, cell type and group