Table 4 MicroRNAs in regulating ferroptosis, pyroptosis, and anoikis in cervical cancer cells

Ferroptosis

miR-4291

ACSL4

In vitro (C33A and CaSki cells)

Inhibits

miR-4291 promotes cervical cancer development by inhibiting ferroptosis by targeting ACSL4.

[207]

miR-506-3p

CD164

In vitro (C33A and Hela cells)

Promotes

miR-506-3p promotes cervical cancer cell ferroptosis by targeting CD164 and by increasing the level of MDA, lipid ROS, and iron.

[198]

miR-193a-5p

(Down)

GPX4

Human (Cervical cancer tissues), In vitro (HeLa and SiHa cells)

Promotes

miR-193a-5p enhances cervical cancer cell ferroptosis by targeting GPX4.

[201]

miR-515-5p, miR-409-3P and miR-375

SLC7A11

In vitro (HeLa cells)

Promotes

miR-515-5p, miR-409-3P and miR-375 maybe promote cervical cancer cell ferroptosis by targeting SLC7A11.

[199]

Pyroptosis

miR-214

-

In vitro (Hela, SiHa, and HCC94 cells)

Promotes

miR-214 induces the pyroptosis of cervical cancer cells by regulating NLRP3 expression levels.

[213]

miR-124

SIRT1

In vitro (HeLa cells)

Inhibits

miR-124 alleviates the cervical cancer pyroptosis by targeting SIRT1.

[214]

Anoikis

miR-525-5p

(Down)

UBE2C

In vitro (HeLa cells)

Inhibition

miR-525-5p enhances the anoikis of cervical cancer cells maybe via negatively regulating UBE2C levels.

[221]