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Fig. 2 | Cancer Cell International

Fig. 2

From: Liquid biopsy-derived extracellular vesicle protein biomarkers for diagnosis and prognostic assessment of lung squamous cell carcinoma

Fig. 2

Characterization of enriched EVs in plasma and comparison with pure EVs. (A) Transmission electron microscopy images of EVs isolated with NaY from BLD plasma. (B) EV size distribution, particle concentration and mode size in BLD plasma as determined by nanoparticle tracking analysis. (C) Plasma EVs from LUSC patients and BLD patients express EV-positive (CD63, CD9, and TSG101) and EV-negative (GRP94) biomarkers, as indicated by Western blot (WB) analysis. (D) Number of proteins detected in pure EVs and enriched EVs in plasma. (E) The overlap of protein IDs detected in pure EVs and enriched EVs in plasma. (F) Quantitative MS intensities of EV-related biomarkers detected in pure EVs and enriched EVs in plasma

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Cancer Cell International

ISSN: 1475-2867

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