Fig. 4

Identification of tumor-associated EV signatures and proteins capable of differentiating LUSC from BLD. (A) Venn diagrams showing the number of proteins with significantly increased levels in both tumor tissue and LUSC EVs (NAT: normal adjacent tissue). (B) Venn diagrams showing the number of proteins with significantly decreased levels in both tumor tissue and LUSC-derived EVs. (C) Heatmap and diagnostic value of EV proteins altered in patients with LUSC relative to those with BLD