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Fig. 7 | Cancer Cell International

Fig. 7

From: Liquid biopsy-derived extracellular vesicle protein biomarkers for diagnosis and prognostic assessment of lung squamous cell carcinoma

Fig. 7

Subtyping of LUSC and associations with clinical outcomes. (A) ssGSEA (C2: curated gene sets, KEGG subset of canonical pathways) revealed the pathways that were significantly enriched in the proteomic subtypes. (B) Proteins in which complement and coagulation cascades pathways were enriched that were differentially expressed between the two proteomic subtypes. (C) Proteins in which non-small cell lung cancer–related pathways were enriched that were differentially expressed between the two proteomic subtypes. (D) The association between risk stratification and clinical information of the patients. Fisher’s exact test was used for categorical variables: sex, differentiation status, smoking status, and TNM stage

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Cancer Cell International

ISSN: 1475-2867

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