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Fig. 2 | Cancer Cell International

Fig. 2

From: Clinicopathological characterization of Switch/Sucrose-non-fermentable (Swi/Snf) complex (ARID1A, SMARCA2, SMARCA4)-deficient endocervical adenocarcinoma

Fig. 2

The microscopic representative pictures with significant differences in morphology in Swi/Snf-deficient ECA. (A-B) Swi/Snf-deficient ECA was poorly differentiated, exhibiting medullary features and marked nuclear pleomorphism, with some nuclei showing vacuolar changes (red arrows). (C-E) The stroma frequently demonstrated necrosis, lymphocytic infiltration (including stromal tumor-infiltrating lymphocytes (sTILs), peritumoral lymphocytic aggregation, and formation of tertiary lymphoid structures (TLS). (F-J) In contrast, Swi/Snf-intact ECA rarely exhibited these morphological features

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Cancer Cell International

ISSN: 1475-2867

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