Table 3 Expressions of immune markers of Swi/Snf-deficient ECAs
Markers | Total (n = 604) | Swi/Snf-intact (n = 568) | Swi/Snf-deficient (n = 36) | P |
|---|---|---|---|---|
CD3 (cells/mm2) | 0.004 | |||
Median (range) | 299.58(5.56-3055.56) | 291.67(5.56-3055.56) | 437.50(41.67-1729.17) | |
CD4 (cells/mm2) | 0.164 | |||
Median (range) | 201.39(0-2083.33) | 199.31(0-2083.33) | 260.42(23.30-1916.67) | |
CD8 (cells/mm2) | < 0.001 | |||
Median (range) | 171.65(0-5111.11) | 166.67(0-2375) | 363.20(15-5111.11) | |
CD15 (cells/mm2) | 0.349 | |||
Median (range) | 50.21(0-2083.33) | 50(0-2083.33) | 80.07(0-1666.67) | |
CD20 (cells/mm2) | 0.161 | |||
Median (range) | 20.83(0-2083.33) | 20.83(0-2083.33) | 29.86(0-2083.33) | |
CD38 (cells/mm2) | < 0.001 | |||
Median (range) | 100.69(0-3333.33) | 93.75(0-3333.33) | 241.67(0-1875) | |
CD56 (cells/mm2) | 0.009* | |||
Median (range) | 0(0-208.33) | 0(0-208.33) | 0(0-138.89) | |
CD68 (cells/mm2) | < 0.001 | |||
Median (range) | 33.33(0-833.33) | 31.25(0-833.3) | 73.82(0-347.22) | |
FOXP3 (cells/mm2) | 0.851 | |||
Median (range) | 29.17(0-666.67) | 29.17(0-666.67) | 26.39(0-479.17) | |
PD-1 (cells/mm2) | 0.003 | |||
Median (range) | 17.78(0-833.33) | 16.67(0-625) | 57.64(0-833.33) | |
PD-L1 CPS, n (%) | < 0.001 | |||
< 1 | 266(44.0) | 261(46.0) | 5(13.9) | |
≥ 1 | 338(56.0) | 307(54.0) | 31(86.1) |